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Pragmatic trials are those that are designed to inform the real-world practice of clinical. They are usually focused on the practical aspects of the study design, including the recruitment and consent process as well as adherence to the use of standard equipment.

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A pragmatic study that involves a variety investigators and includes participants from different geographical areas is the Home Blood Pressure Management study (HBPM). This kind of heterogeneity is required for practical trials to be valid and helps to reduce bias in the results. A high degree of heterogeneity,  [[http://daojianchina.com/home.php?mod=space&uid=4670767|프라그마틱 체험]] however, can cause problems with the design of the trial.

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The purpose of pragmatic trials is to mimic real-life scenarios and to achieve maximum credibility externally. They are usually requested by practitioners and policy makers to guide their decision-making. They are also a good method to determine the cause-effect relationship between an intervention and its outcomes. They should, however, not be used to replace explanatory studies.

The pragmatism idea is controversial, and there are concerns about whether pragmatic trials should replace or complement them. Schwartz and Lellouch1 suggested the distinction between explanation trials, which prove the clinical or physiological hypothesis and pragmatic trials that inform policy and practice decisions. They also suggested the framework for pragmatic trials, dubbed PRECIS.2 This tool attempted to define the elements of a practical trial, including the recruitment process, the design and  [[https://jisuzm.com/home.php?mod=space&uid=5290472|프라그마틱 슬롯버프]] 사이트 [[[https://www.play56.net/home.php?mod=space&uid=3517189|websites]]] delivery of the intervention, as well as the follow-up.

There is a positive trend in the number of pragmatic trials that are published. A recent Medline search using the terms pragmatic and naturalistic, restricted to randomized controlled trials (RCTs), yielded 34 articles, which are shown in red in Figure 2. This indicates that the health sciences community is becoming increasingly sensitized to the subject of pragmatics. However, it is important to remember that the majority of these trials were conducted in primary care settings.